Anti-DM1/DM4 (Maytansine) Monoclonal Antibody (mAb)
Anti-DM1/DM4 (Maytansinoid) monoclonal antibody (mAb)
The anti-DM1/DM4 monoclonal antibody for ADC uses maytansinoid as a highly toxic payload for antibody-drug conjugates.
It effectively delivers DM1/DM4 into cancer cells, inhibits microtubule formation, stops the cell cycle, and induces apoptosis only in cancer cells, while normal cells are less affected, thereby achieving targeted anti-cancer therapy.
View the application of maytansinoid (DM1/DM4) in ADC
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Order Information
| Catalog No. | Product Name | Specification | Price (USD) | Shipping/Handling fee |
|---|---|---|---|---|
| GTU-Bios-Maytansinoids-Ab-1 | Anti-DM1/DM4 (Maytansinoid) Human Monoclonal Antibody (mAb) | 1mg | USD 1,690.00 | 360 |
| GTU-Bios-Maytansinoids-Ab-2 | Anti-DM1/DM4 (Maytansinoid) Mouse Monoclonal Antibody (mAb) | 1mg | USD 1,690.00 | 360 |
| GTU-Bios-Maytansinoids-Ab-3 | Anti-DM1/DM4 (Maytansinoid) Mouse Monoclonal Antibody (mAb) | 1mg | USD 1,690.00 | 360 |
| GTU-Bios-Maytansinoids-Ab-1 | Anti-DM1/DM4 (Maytansinoid) Human Monoclonal Antibody (mAb) | 100μg | USD 310.00 | 60 |
| GTU-Bios-Maytansinoids-Ab-2 | Anti-DM1/DM4 (Maytansinoid) Mouse Monoclonal Antibody (mAb) | 100μg | USD 310.00 | 60 |
| GTU-Bios-Maytansinoids-Ab-3 | Anti-DM1/DM4 (Maytansinoid) Mouse Monoclonal Antibody (mAb) | 100μg | USD 310.00 | 60 |
(Available sizes: 1mg | 10mg | 100mg)
Description
Anti-DM1/DM4 (Maytansinoid) human monoclonal antibody (Human mAb)
Catalog No.
GTU-Bios-Maytansinoids-Ab-1
Product Name
Anti-DM1/DM4 (Maytansinoid) human monoclonal antibody (mAb)
Target
Maytansinoid (DM1/DM4)
Expression Platform
Mammalian cell
Isotype
Human IgG1
Biological Activity Verification
Maytansinoid (DM1/DM4) binding assay, competitive ELISA (Competitive immunoassay validation)
Tag
hFc
Product Description
Anti-Maytansinoid (DM1/DM4) monoclonal antibody expressed in mammalian cells.
Species Source
Human
Purity
≥95% (SDS-PAGE)
Application
Competitive immunoassay validation (Competitive ELISA), PK & PD analysis
Formulation and Reconstitution
Lyophilized powder (PSB2 or PBS). Reconstitute with 0.9% NaCl (PSB2) or ddH2O (PBS).
Storage Conditions
-20°C to -80°C, avoid repeated freeze-thaw cycles
Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (Mouse mAb)
Catalog No.
GTU-Bios-Maytansinoids-Ab-2, GTU-Bios-Maytansinoids-Ab-3
Product Name
Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody (mAb)
Target
Maytansinoid (DM1/DM4)
Expression Platform
Mammalian cell
Isotype
Mouse IgG (Mouse IgG)
Biological Activity Verification
Maytansinoid (DM1/DM4) binding assay, competitive ELISA (Competitive immunoassay validation)
Tag
mFc
Product Description
Anti-DM1/DM4 (Maytansinoid) mouse monoclonal antibody, expressed by mammalian cells.
Species Source
Mouse
Purity
≥95% (SDS-PAGE)
Application
Competitive immunoassay validation (Competitive ELISA), PK & PD analysis
Formulation and Reconstitution
Lyophilized powder (PSB2 or PBS). Reconstitute with 0.9% NaCl (PSB2) or ddH2O (PBS).
Storage Conditions
-20°C to -80°C, avoid repeated freeze-thaw cycles
Validation Data (Validation Data)
See more validation data and case studies for this product.
Get full validation reportAssociated Products
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|---|---|---|---|
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