Anti-DXd/Exatecan monoclonal antibody (mAb)
Anti-DXd/Exatecan monoclonal antibody (mAb)
Using our specific anti-DXd/Exatecan monoclonal antibody, you can effectively target and accurately quantify DXd/Exatecan-related ADCs, because our product facilitates large-scale pharmacokinetic evaluation.
Such evaluations are crucial for understanding the lifecycle of ADCs, providing valuable insights into their absorption, distribution, and elimination phases, thereby helping to optimize the use of ADC-based therapies.
View Technical Information (Technical Information)
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Order Information
| Catalog No. | Product Name | Specification | Price (USD) | Inquiry |
|---|---|---|---|---|
| GTU-Bios-DXd-Ab-1 | Anti-DXd/Exatecan humanized monoclonal antibody (mAb) | 1mg | USD 1,690.00 | |
| GTU-Bios-DXd-Ab-2 | Anti-DXd/Exatecan mouse monoclonal antibody (mAb) | 1mg | USD 1,690.00 | |
| GTU-Bios-DXd-Ab-3 | Anti-DXd/Exatecan mouse monoclonal antibody (mAb) | 1mg | USD 1,690.00 | |
| GTU-Bios-DXd-Ab-1 | Anti-DXd/Exatecan humanized monoclonal antibody (mAb) | 100μg | USD 310.00 | |
| GTU-Bios-DXd-Ab-2 | Anti-DXd/Exatecan mouse monoclonal antibody (mAb) | 100μg | USD 310.00 | |
| GTU-Bios-DXd-Ab-3 | Anti-DXd/Exatecan mouse monoclonal antibody (mAb) | 100μg | USD 310.00 |
(Available sizes: 1mg | 10mg | 100mg)
Description
Anti-DXd/Exatecan human monoclonal antibody (Human mAb)
Catalog No.
GTU-Bios-DXd-Ab-1
Product Name
Anti-DXd/Exatecan human monoclonal antibody (mAb)
Target
Deruxtecan (DXd) / Exatecan
Expression Platform
Mammalian cell
Isotype
Human IgG1
Biological Activity Verification
Deruxtecan (DXd) / Exatecan binding assay;
Competitive immunoassay verification (Competitive ELISA) in DXd/Exatecan level testing.
Competitive immunoassay verification (Competitive ELISA) in DXd/Exatecan level testing.
Tag
hFc
Product Description
Anti-Deruxtecan (DXd)/Exatecan monoclonal antibody, expressed in mammalian cells.
Species Source
Human
Purity
≥95% (SDS-PAGE)
Application
Competitive immunoassay verification (Competitive ELISA) and other immunoassays;
PK & PD analysis of DXd & Exatecan payload in antibody-drug conjugates (ADC).
PK & PD analysis of DXd & Exatecan payload in antibody-drug conjugates (ADC).
Formulation and Reconstitution
Lyophilized from GM Protein Stabilization Buffer 2 (PSB2, proprietary) or PBS (pH7.4);
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
Storage Conditions
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Anti-DXd/Exatecan mouse monoclonal antibody (Mouse mAb)
Catalog No.
GTU-Bios-DXd-Ab-2, GTU-Bios-DXd-Ab-3
Product Name
Anti-DXd/Exatecan mouse monoclonal antibody (mAb)
Target
Deruxtecan (DXd) / Exatecan
Expression Platform
Mammalian cell
Isotype
Mouse IgG
Biological Activity Verification
Deruxtecan (DXd) / Exatecan binding assay;
Competitive immunoassay verification (Competitive ELISA) in DXd/Exatecan level testing.
Competitive immunoassay verification (Competitive ELISA) in DXd/Exatecan level testing.
Tag
mFc
Product Description
Anti-Deruxtecan (DXd)/Exatecan mouse monoclonal antibody, expressed in mammalian cells.
Species Source
Mouse
Purity
≥95% (SDS-PAGE)
Application
Competitive immunoassay verification (Competitive ELISA) and other immunoassays;
PK & PD analysis of DXd & Exatecan payload in antibody-drug conjugates (ADC).
PK & PD analysis of DXd & Exatecan payload in antibody-drug conjugates (ADC).
Formulation and Reconstitution
Lyophilized from GM Protein Stabilization Buffer 2 (PSB2, proprietary) or PBS (pH7.4);
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
Storage Conditions
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Validation Data (Validation Data)
See more validation data and case studies for this product.
Get full validation reportAssociated Products
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Antibody-Drug Conjugate (ADC) Knowledge Base
- ADC Panorama: Production, Mechanism of Action (MOA), FDA-Approved Antibodies and Functional Analysis
- What is an Antibody-Drug Conjugate (ADC)?
- ADC Clinical Application Progress (Approved/BLA/Clinical Phases)
- ADC Key Components: Antibodies and Targets
- ADC Key Components: Linker Structure and Mechanism
- ADC Key Components: Toxin/Payload (Classification and Function)
- Payload: Microtubule-Disrupting Agents (Classification and Function)
- Payload: DNA-Damaging Agents (Classification and Function)
- Payload: Innovative Drugs (Classification and Function)
- Bioconjugation Technology: Chemical-Based Site-Specific In Situ Antibody Modification
- Endogenous Amino Acid Conjugation and Disulfide Rebridging Strategy
- Glycan Coupling
- Engineered Antibody Site-Specific Bioconjugation and Enzymatic Methods
- Bioconjugation of Engineered Non-Natural Amino Acids
- ADC Production, Quality Control and Functional Analysis Review
- ADC Product Data
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