Anti-PBD (pyrrolobenzodiazepine) monoclonal antibody (mAb)
Anti-PBD (Pyrrolobenzodiazepine) monoclonal antibody (mAb)
Pharmacokinetic advantages of our anti-PBD monoclonal antibody: Based on this concept, our anti-PBD monoclonal antibody will be ideally suited for providing pharmacokinetic characterization information of antibody-drug conjugates (ADC).
The advantage of this antibody is that it can more accurately evaluate the binding mode of ADC to PBD and study its effects and outcomes in more detail.
Understanding the application of pyrrolobenzodiazepine (PBD) in ADCs.
MSDS
Order Information
| Catalog No. | Product Name | Specification |
|---|---|---|
| GTU-Bios-PBD-Ab-1 | Anti-PBD (pyrrolobenzodiazepine) human monoclonal antibody (mAb) | 1mg |
| GTU-Bios-PBD-Ab-2 | Anti-PBD (pyrrolobenzodiazepine) mouse monoclonal antibody (mAb) | 1mg |
| GTU-Bios-PBD-Ab-3 | Anti-PBD (pyrrolobenzodiazepine) mouse monoclonal antibody (mAb) | 1mg |
Size： 1mg | 10mg | 100mg
Description
Anti-PBD (pyrrolobenzodiazepine) human monoclonal antibody (mAb)>
Catalog No.
GTU-Bios-PBD-Ab-1
Product Name
Anti-PBD (pyrrolobenzodiazepine) human monoclonal antibody (mAb)
Target
Pyrrolobenzodiazepines (PBD)
Expression Platform
Mammalian cell
Isotype
Human IgG1
Biological Activity Verification
Pyrrolobenzodiazepine (PBD) binding, competitive immunoassay validation (competitive ELISA) in the application of pyrrolobenzodiazepine (PBD) level testing.
Tag
hFc
Product Description
Anti-pyrrolobenzodiazepine (PBD) monoclonal antibody expressed by mammalian cells.
Species Source
Human
Purity
Purity: ≥95% (SDS-PAGE)
Application
Competitive immunoassay validation (competitive ELISA) and other immunoassays, PK and PD assays for PBD payloads of antibody-drug conjugates (ADC).
Formulation and Reconstitution
Lyophilized from GM's Protein Stabilization Buffer 2 (PSB2, confidential composition) or PBS (pH7.4);
For PSB2, reconstitute with 0.9% sodium chloride;
For PSB2, reconstitute with 0.9% sodium chloride;
For PSB2, reconstitute with 0.9% sodium chloride;
For PSB2, reconstitute with 0.9% sodium chloride;
Storage Conditions
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Anti-PBD (pyrrolobenzodiazepine) mouse monoclonal antibody (mAb)
Catalog No.
GTU-Bios-PBD-Ab-2, GTU-Bios-PBD-Ab-3
Product Name
Anti-PBD (pyrrolobenzodiazepine) mouse monoclonal antibody (mAb)
Target
Pyrrolobenzodiazepines (PBD)
Expression Platform
Mammalian cell
Isotype
Mouse IgG
Biological Activity Verification
Pyrrolobenzodiazepine (PBD) binding, competitive immunoassay validation (competitive ELISA) in the application of pyrrolobenzodiazepine (PBD) level testing.
Tag
mFc
Product Description
Anti-pyrrolobenzodiazepine (PBD) mouse monoclonal antibody (mAb) expressed by mammalian cells.
Species Source
Mouse
Purity
Purity: ≥95% (SDS-PAGE)
Application
Competitive immunoassay validation (competitive ELISA) and other immunoassays, PK and PD assays for PBD payloads of antibody-drug conjugates (ADC).
Formulation and Reconstitution
Lyophilized from GM Protein Stabilization Buffer 2 (PSB2, proprietary) or PBS (pH7.4);
PSB2 reconstitute with 0.9% sodium chloride;
PBS reconstitute with ddH2O.
PSB2 reconstitute with 0.9% sodium chloride;
PBS reconstitute with ddH2O.
Storage Conditions
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
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