Anti-SN-38 (7-ethyl-10-hydroxycamptothecin) Monoclonal Antibody (mAb)
Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) monoclonal antibody (mAb)
PK Studies: Our innovative anti-SN-38 monoclonal antibody is developed for precision in pharmacokinetic (PK) studies of antibody-drug conjugates (ADCs).
It enables a better understanding of the distribution and metabolism of SN-38 conjugated ADCs, thereby helping researchers to identify improved ADC therapeutic strategies.
See the application of 7-Ethyl-10-hydroxycamptothecin (SN-38) in ADCs
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Order Information
| Catalog No. | Product Name | Specification | Inquiry |
|---|---|---|---|
| GTU-Bios-SN-38-Ab-1 | Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) human monoclonal antibody (mAb) | 1mg | |
| GTU-Bios-SN-38-Ab-2 | Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb) | 1mg | |
| GTU-Bios-SN-38-Ab-3 | Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb) | 1mg | |
| GTU-Bios-SN-38-Ab-1 | Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) human monoclonal antibody (mAb) | 100μg | |
| GTU-Bios-SN-38-Ab-2 | Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb) | 100μg | |
| GTU-Bios-SN-38-Ab-3 | Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb) | 100μg |
(Available sizes: 1mg | 10mg | 100mg)
Description
Anti-SN-38 human monoclonal antibody (Human mAb)
Catalog No.
GTU-Bios-SN-38-Ab-1
Product Name
Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) human monoclonal antibody (mAb)
Target
7-Ethyl-10-hydroxycamptothecin (SN-38)
Expression Platform
Mammalian cell
Isotype
Human IgG1
Biological Activity Verification
SN-38 binding assay;
Validated by competitive immunoassay in SN-38 level testing (competitive ELISA).
Validated by competitive immunoassay in SN-38 level testing (competitive ELISA).
Tag
hFc
Product Description
Anti-SN-38 monoclonal antibody expressed in mammalian cells.
Species Source
Human
Purity
≥95% (SDS-PAGE)
Application
Competitive immunoassay verification (Competitive ELISA) and other immunoassays;
PK & PD analysis of SN-38 payload in antibody-drug conjugates (ADC).
PK & PD analysis of SN-38 payload in antibody-drug conjugates (ADC).
Formulation and Reconstitution
Lyophilized from GM Protein Stabilization Buffer 2 (PSB2, proprietary) or PBS (pH7.4);
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
Storage Conditions
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Anti-SN-38 mouse monoclonal antibody (Mouse mAb)
Catalog No.
GTU-Bios-SN-38-Ab-2, GTU-Bios-SN-38-Ab-3
Product Name
Anti-SN-38 (7-Ethyl-10-hydroxycamptothecin) mouse monoclonal antibody (mAb)
Target
7-Ethyl-10-hydroxycamptothecin (SN-38)
Expression Platform
Mammalian cell
Isotype
Mouse IgG (Mouse IgG)
Biological Activity Verification
SN-38 binding assay;
Validated by competitive immunoassay in SN-38 level testing (competitive ELISA).
Validated by competitive immunoassay in SN-38 level testing (competitive ELISA).
Tag
mFc
Product Description
Anti-SN-38 mouse monoclonal antibody, expressed in mammalian cells.
Species Source
Mouse
Purity
≥95% (SDS-PAGE)
Application
Competitive immunoassay verification (Competitive ELISA) and other immunoassays;
PK & PD analysis of SN-38 payload in antibody-drug conjugates (ADC).
PK & PD analysis of SN-38 payload in antibody-drug conjugates (ADC).
Formulation and Reconstitution
Lyophilized from GM Protein Stabilization Buffer 2 (PSB2, proprietary) or PBS (pH7.4);
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
PSB2 reconstitute with 0.9% sodium chloride;
Reconstitute PBS with deionized water (ddH2O).
Storage Conditions
Store under sterile conditions at -20°C to -80°C. Avoid repeated freeze-thaw cycles.
Validation Data (Validation Data)
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